Structure of PDB 6f1c Chain D

Receptor sequence
>6f1cD (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
EPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENC
AYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFS
NEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLH
DDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVV
VTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKS
NALDIIFQTDLTGQKKGWKLRYHGDP
3D structure
PDB6f1c Structure of the C1r-C1s interaction of the C1 complex of complement activation.
ChainD
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.42: complement subcomponent C1s.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D D53 S97 D98 S100 N101 D53 S97 D98 S100 N101
BS02 CA D D116 I117 E119 F135 G137 G138 D116 I117 E119 F135 G137 G138
BS03 CA D D221 D260 T262 G263 Q264 D221 D260 T262 G263 Q264
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:6f1c, PDBe:6f1c, PDBj:6f1c
PDBsum6f1c
PubMed29311313
UniProtP09871|C1S_HUMAN Complement C1s subcomponent (Gene Name=C1S)

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