Structure of PDB 6dmx Chain D

Receptor sequence
>6dmxD (length=81) Species: 10090 (Mus musculus) [Search protein sequence]
WHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMY
ESANSRDEYYHLLAEKIYKIQKELEEKRRSR
3D structure
PDB6dmx Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain.
ChainD
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D D598 H602 L603 K606 R646 Y650 H651 A654 E655 I657 Y658 Q661 D8 H12 L13 K16 R56 Y60 H61 A64 E65 I67 Y68 Q71
Gene Ontology
Molecular Function
GO:0003712 transcription coregulator activity
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6dmx, PDBe:6dmx, PDBj:6dmx
PDBsum6dmx
PubMed30232260
UniProtP45481|CBP_MOUSE Histone lysine acetyltransferase CREBBP (Gene Name=Crebbp)

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