Structure of PDB 6dhk Chain D

Receptor sequence
>6dhkD (length=496) Species: 9913 (Bos taurus) [Search protein sequence]
DPNFFKMVEGFFDRGASIVEDKLVEDLKTRETEEQKRNRVRGILRIIKPC
NHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVK
ALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKK
GFIGPGVDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQ
GGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFAVQGFGNV
GLHSMRYLHRFGAKCVAVGESDGSIWNPDGIDPKELEDFKLQHGTILGFP
KAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPE
ADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDS
NYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAY
TMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFRVYNEAGVTFT
3D structure
PDB6dhk Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation.
ChainD
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.4.1.3: glutamate dehydrogenase [NAD(P)(+)].
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP D I203 H209 K387 S393 R396 I198 H204 K382 S388 R391
BS02 ADP D H85 R86 A116 D119 R459 K488 V492 H80 R81 A111 D114 R454 K483 V487
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
Biological Process
GO:0006520 amino acid metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6dhk, PDBe:6dhk, PDBj:6dhk
PDBsum6dhk
PubMed12653548
UniProtP00366|DHE3_BOVIN Glutamate dehydrogenase 1, mitochondrial (Gene Name=GLUD1)

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