Structure of PDB 6d06 Chain D

Receptor sequence
>6d06D (length=352) Species: 9606 (Homo sapiens) [Search protein sequence]
LPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKV
ISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNK
DDQKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPIRGQLR
TKIESGYGTIPVRLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILG
SLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNF
SVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLL
RSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFS
LT
3D structure
PDB6d06 A Bump-Hole Approach for Directed RNA Editing.
ChainD
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IHP D N391 I397 R401 K519 R522 S531 K629 Y658 K662 Y668 K672 K690 N73 I79 R83 K171 R174 S183 K281 Y310 K314 Y320 K324 K342
BS02 ZN D H394 C451 C516 H76 C133 C168
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004000 adenosine deaminase activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:6d06, PDBe:6d06, PDBj:6d06
PDBsum6d06
PubMed30581135
UniProtP78563|RED1_HUMAN Double-stranded RNA-specific editase 1 (Gene Name=ADARB1)

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