Structure of PDB 6crn Chain D

Receptor sequence
>6crnD (length=343) Species: 9606 (Homo sapiens) [Search protein sequence]
GRNNEQPGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFD
NPLGMRGEIAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSQQQDC
QELLAFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRND
SIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMPKKPFVKLKDC
IELFTTKEKLEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRY
MRDKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYT
AFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDSS
3D structure
PDB6crn Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.
ChainD
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C448 C451 C502 C167 C170 C219
Gene Ontology
Molecular Function
GO:0004843 cysteine-type deubiquitinase activity
Biological Process
GO:0016579 protein deubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:6crn, PDBe:6crn, PDBj:6crn
PDBsum6crn
PubMed30713027
UniProtQ9Y4E8|UBP15_HUMAN Ubiquitin carboxyl-terminal hydrolase 15 (Gene Name=USP15)

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