Structure of PDB 6cl2 Chain D

Receptor sequence
>6cl2D (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQI
LTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFS
3D structure
PDB6cl2 Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3.
ChainD
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y230 S231 W232 R233 S234 P235 S275 Q276 D278 F282 Y19 S20 W21 R22 S23 P24 S64 Q65 D67 F71
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6cl2, PDBe:6cl2, PDBj:6cl2
PDBsum6cl2
PubMed31334631
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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