Structure of PDB 6cey Chain D

Receptor sequence
>6ceyD (length=293) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
YDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTK
FSGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLT
PEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYI
LLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLD
GNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNID
IEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRT
3D structure
PDB6cey Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2′′)-Ia.
ChainD
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.7.1.190: aminoglycoside 2''-phosphotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP D S214 I224 K226 Y274 I277 F281 H379 I392 D393 S36 I46 K48 Y91 I94 F98 H196 I209 D210
BS02 LIV D D374 S376 D396 Y408 E411 E415 Y448 E451 D191 S193 D213 Y225 E228 E232 Y265 E268
BS03 MG D H379 D393 H196 D210
External links
PDB RCSB:6cey, PDBe:6cey, PDBj:6cey
PDBsum6cey
PubMed29661878
UniProtP0A0C1|AACA_STAAU Bifunctional AAC/APH (Gene Name=aacA-aphD)

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