Structure of PDB 6cav Chain D

Receptor sequence
>6cavD (length=284) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
ATNVKAMKYLIEHYFDNFKVDSIEIIGSSVAYLVNNEYIFKTKFYAKEKA
IYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSE
EEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYND
LTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQD
IVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRT
3D structure
PDB6cav Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2′′)-Ia.
ChainD
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.7.1.190: aminoglycoside 2''-phosphotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP D I224 K226 Y274 I277 F281 H379 I392 D393 I39 K41 Y82 I85 F89 H187 I200 D201
BS02 MG D H379 D393 H187 D201
BS03 84D D D374 S376 D396 Y408 E411 E415 E416 Y448 E451 D182 S184 D204 Y216 E219 E223 E224 Y256 E259
External links
PDB RCSB:6cav, PDBe:6cav, PDBj:6cav
PDBsum6cav
PubMed29661878
UniProtP0A0C1|AACA_STAAU Bifunctional AAC/APH (Gene Name=aacA-aphD)

[Back to BioLiP]