Structure of PDB 6c1t Chain D

Receptor sequence
>6c1tD (length=66) Species: 9606 (Homo sapiens) [Search protein sequence]
RMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLG
NTVDLSSFDFRTGKMM
3D structure
PDB6c1t Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
ChainD
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R188 S189 P191 R209 R40 S41 P43 R61 PDBbind-CN: Kd=3.2uM
BS02 dna D R166 S168 G169 L170 S171 R18 S20 G21 L22 S23 PDBbind-CN: Kd=3.2uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6c1t, PDBe:6c1t, PDBj:6c1t
PDBsum6c1t
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

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