Structure of PDB 6bg0 Chain D

Receptor sequence
>6bg0D (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMH
ILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
3D structure
PDB6bg0 Modifications to a common phosphorylation network provide individualized control in caspases.
ChainD
Resolution2.125 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y204 S205 W206 R207 N208 S209 S249 Y20 S21 W22 R23 N24 S25 S65
BS02 AZI D E190 F193 E6 F9
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6bg0, PDBe:6bg0, PDBj:6bg0
PDBsum6bg0
PubMed29414778
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

[Back to BioLiP]