Structure of PDB 5zz1 Chain D

Receptor sequence
>5zz1D (length=678) Species: 85995 (Mycothermus thermophilus) [Search protein sequence]
SPLAAYEVDDSTGYLTSDVGGPIQDQTSLKAGIRGPTLLEDFMFRQKIQH
FDHERVPERAVHARGAGAHGTFTSYADWSNITAASFLNATGKQTPVFVRF
STVAGSRGSADTARDVHGFATRFYTDEGNFDIVGNNIPVFFIQDAIQFPD
LIHSVKPRPDNEIPQAATAHDSAWDFFSQQPSTMHTLFWAMSGHGIPRSY
RHMDGFGVHTFRFVKDDGSSKLIKWHFKSRQGKASLVWEEAQVLSGKNAD
FHRQDLWDAIESGNGPEWDVCVQIVDESQAQAFGFDLLDPTKIIPEEYAP
LTKLGLLKLDRNPTNYFAETEQVMFQPGHIVRGIDFTEDPLLQGRLFSYL
DTQLNRNGGPNFEQLPINMPRVPIHNNNRDGAGQMFIHRNKYPYTPNTLN
SGYPRQANQNAGRGFFTAPGRTASGALVREVSPTFNDHWSQPRLFFNSLT
PVEQQFLVNAMRFEISLVKSEEVKKNVLTQLNRVSHDVAVRVAAAIGLGA
PDADDTYYHNNKTAGVSIVGSGPLPTIKTLRVGILATTSESSALDQAAQL
RTRLEKDGLVVTVVAETLREGVDQTYSTADATGFDGVVVVDGAAALFAST
ASSPLFPTGRPLQIFVDAYRWGKPVGVCGGKSSEVLDAADVPEDGDGVYS
EESVDMFVEEFEKGLATFRFTDRFALDS
3D structure
PDB5zz1 Identification of the site of oxidase substrate binding in Scytalidium thermophilum catalase.
ChainD
Resolution1.91 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) H82 N155 Q346
Catalytic site (residue number reindexed from 1) H62 N135 Q326
Enzyme Commision number 1.11.1.6: catalase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3TR D F626 P627 F606 P607 MOAD: Ki=0.021M
BS02 HDD D R79 V81 H82 R119 V153 G154 N155 F160 F168 V228 H229 F345 L361 R365 S368 Y369 T372 R59 V61 H62 R99 V133 G134 N135 F140 F148 V208 H209 F325 L341 R345 S348 Y349 T352
BS03 3TR D P158 I313 I314 E316 P138 I293 I294 E296 MOAD: Ki=0.021M
BS04 CA D R178 H190 D191 S192 R158 H170 D171 S172
Gene Ontology
Molecular Function
GO:0004096 catalase activity
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006979 response to oxidative stress
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5zz1, PDBe:5zz1, PDBj:5zz1
PDBsum5zz1
PubMed30289408
UniProtM4GGR7

[Back to BioLiP]