Structure of PDB 5yu1 Chain D

Receptor sequence
>5yu1D (length=344) Species: 38300 (Streptomyces pristinaespiralis) [Search protein sequence]
METWVLGRRDVAEVVAAVGRDELMRRIIDRLTGGLAEIGRGERHLSPLRG
GLERSEPVPGIWEWMPHREPGDHITLKTVGYSPANPARFGLPTILGTVAR
YDDTTGALTALMDGVLLTALRTGAASAVASRLLARPDSHTLGLIGTGAQA
VTQLHALSLVLPLQRALVWDTDPAHRESFARRAAFTGVSVEIAEPARIAA
EADVISTATSVAVGQGPVLPDTGVREHLHINAVGADLVGKTELPLGLLER
AFVTADHPEQALREGECQQLSADRLGPQLAHLCADPAAAAGRQDTLSVFD
STGFAFEDALAMEVFLEAAAERDLGIRVGIEHHPGDALDPYALQ
3D structure
PDB5yu1 Structural Basis for Recognition of L-lysine, L-ornithine, and L-2,4-diamino Butyric Acid by Lysine Cyclodeaminase.
ChainD
Resolution1.923 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.3.1.12: ornithine cyclodeaminase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD D Y81 T93 I94 T122 G147 A148 Q149 D170 T171 A208 T209 S210 V211 V233 G234 A235 S301 T302 G303 Y81 T93 I94 T122 G147 A148 Q149 D170 T171 A208 T209 S210 V211 V233 G234 A235 S301 T302 G303
BS02 YCP D R49 E63 M65 K77 R121 A235 T302 R49 E63 M65 K77 R121 A235 T302
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008473 ornithine cyclodeaminase activity
GO:0016829 lyase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:5yu1, PDBe:5yu1, PDBj:5yu1
PDBsum5yu1
PubMed29629557
UniProtD9UBW0

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