Structure of PDB 5ypf Chain D

Receptor sequence
>5ypfD (length=45) Species: 9606 (Homo sapiens) [Search protein sequence]
DVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFP
3D structure
PDB5ypf Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
ChainD
Resolution2.951 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
3.6.4.10: non-chaperonin molecular chaperone ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C4 C7 C27 C30 C4 C7 C27 C30
BS02 ZN D C18 C21 H36 H39 C18 C21 H36 H39
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5ypf, PDBe:5ypf, PDBj:5ypf
PDBsum5ypf
PubMed30120248
UniProtP11021|BIP_HUMAN Endoplasmic reticulum chaperone BiP (Gene Name=HSPA5);
Q13501|SQSTM_HUMAN Sequestosome-1 (Gene Name=SQSTM1)

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