Structure of PDB 5y4q Chain D

Receptor sequence
>5y4qD (length=270) Species: 353153 (Trypanosoma cruzi strain CL Brener) [Search protein sequence]
ELISGGWFREENDPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTV
MALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVL
RHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQ
TPDNTYDVVIIDTFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIR
ETGFASVQYALMHVPTYIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYY
DSEMHKASFALPRFARHINN
3D structure
PDB5y4q Discovering a hidden allosteric binding site by combining molecular simulations and X-ray crystallography
ChainD
Resolution2.07 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.5.1.16: spermidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 S4M D Q64 H74 G95 D98 D118 I119 G150 D168 T169 Q58 H68 G89 D92 D112 I113 G144 D162 T163
BS02 8OF D E14 W53 I63 Y73 Q201 T236 Y237 E10 W47 I57 Y67 Q181 T216 Y217
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004766 spermidine synthase activity
GO:0016740 transferase activity
Biological Process
GO:0006596 polyamine biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5y4q, PDBe:5y4q, PDBj:5y4q
PDBsum5y4q
PubMed37521650
UniProtQ4DA73

[Back to BioLiP]