Structure of PDB 5xox Chain D

Receptor sequence
>5xoxD (length=229) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KFGYVRQFETHDVILPQCYIVVRIDGKKFHEFSKFYEFAKPNDENALKLM
NACAKNLVLKYKNDIILAFGESDEYSFILKSSTTLFNRRKDKLATLFGSF
FTSNYVALWAKFFPEKPLNIKHLPYFDSRCVAYPNLQTIKDYLSWRYVDT
HINNLYNTTFWQLIIKCGLTPQESEKKLCGTFSNEKQEILFSECGINYNN
EPEMFKKGSLVTRKGEILHINVIAQIDEL
3D structure
PDB5xox Crystal structure of tRNA(His) guanylyltransferase from Saccharomyces cerevisiae
ChainD
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.79: tRNA(His) guanylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP D G30 K32 F33 H34 S37 F42 K44 N46 D47 S76 D77 G26 K28 F29 H30 S33 F38 K40 N42 D43 S72 D73
BS02 MG D D29 G30 D77 D25 G26 D73
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005525 GTP binding
GO:0008193 tRNA guanylyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0097748 3'-5' RNA polymerase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0099116 tRNA 5'-end processing
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5xox, PDBe:5xox, PDBj:5xox
PDBsum5xox
PubMed28623126
UniProtP53215|THG1_YEAST tRNA(His) guanylyltransferase (Gene Name=THG1)

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