Structure of PDB 5x45 Chain D

Receptor sequence
>5x45D (length=136) Species: 463676 (Rhinovirus C) [Search protein sequence]
GPSDMFVHTRDAIYKCAHLTNPTDETILLALTADLQVDSTNVPGPDVIPC
CDCTAGCYYSRSKDRYFPVECVSHDWYEIQESGYYPKHIQYNLLIGEGHC
EPGDCGGKLLCKHGVIGMITAGGDNHVAFTDLRPYS
3D structure
PDB5x45 Structural view of the 2A protease from human rhinovirus C15.
ChainD
Resolution2.602 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN D C51 C53 C111 H113 C51 C53 C111 H113
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0016032 viral process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:5x45, PDBe:5x45, PDBj:5x45
PDBsum5x45
PubMed29633974
UniProtE5D8F2|POLG_HRV15 Genome polyprotein

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