Structure of PDB 5wjq Chain D

Receptor sequence

>5wjqD (length=281) Species: 10090 (Mus musculus) [Search protein sequence]

GSEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLL
RHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYS
CASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKE
CGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDR
PHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQK
IHTGEKPYKCQQCGKAFIRGSHLTQHQRIHT

3D structure

PDB

5wjq DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.

Chain

Resolution

2.794 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	D	R411 R430 H433 R436 H437 I440 Y458 K482 K501 H517 R520 H521 S523 K538 F540 R541 R542 E545 R548 R576 H577 R585 R598 E601 S608 R626 E629 R632 H633 R654 H657 H661	R26 R45 H48 R51 H52 I55 Y73 K97 K116 H132 R135 H136 S138 K153 F155 R156 R157 E160 R163 R191 H192 R200 R213 E216 S223 R241 E244 R247 H248 R269 H272 H276
BS02	dna	D	S402 Q405 D459 C486 S488 S514 S516 H517 T572 F575 K579 S628	S17 Q20 D74 C101 S103 S129 S131 H132 T187 F190 K194 S243
BS03	ZN	D	C393 C396 H409 H413	C8 C11 H24 H28
BS04	ZN	D	C421 C424 H437 H441	C36 C39 H52 H56
BS05	ZN	D	C449 C452 H465 H469	C64 C67 H80 H84
BS06	ZN	D	C480 H493 H497	C95 H108 H112
BS07	ZN	D	C505 C508 H521 H525	C120 C123 H136 H140
BS08	ZN	D	C533 H549 H553	C148 H164 H168
BS09	ZN	D	C561 C564 H577 H581	C176 C179 H192 H196
BS10	ZN	D	C589 C592 H605 H609	C204 C207 H220 H224
BS11	ZN	D	C617 C620 H633 H637	C232 C235 H248 H252
BS12	ZN	D	C645 C648 H661 H665	C260 C263 H276 H280

External links

PDB	RCSB:5wjq, PDBe:5wjq, PDBj:5wjq
PDBsum	5wjq
PubMed	29551271
UniProt	E9PYI1\|ZN568_MOUSE Zinc finger protein 568 (Gene Name=Znf568)

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