Structure of PDB 5w7b Chain D

Receptor sequence
>5w7bD (length=412) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDS
DKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIIL
LGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLD
SENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPA
IVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHV
ILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWM
SANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQ
KMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNP
QIEEVFGDQGGH
3D structure
PDB5w7b Crystal structure of the mammalian lipopolysaccharide detoxifier.
ChainD
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.77: acyloxyacyl hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D D183 D185 D187 Y189 D204 D207 D25 D27 D29 Y31 D46 D49
BS02 CA D D185 D187 D204 N206 D209 V212 D27 D29 D46 N48 D51 V54
BS03 CA D D222 D226 N228 N230 I232 E244 D64 D68 N70 N72 I74 E86
BS04 PO4 D G340 N372 R378 G177 N209 R215
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0050528 acyloxyacyl hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5w7b, PDBe:5w7b, PDBj:5w7b
PDBsum5w7b
PubMed29343645
UniProtO18823|AOAH_RABIT Acyloxyacyl hydrolase (Gene Name=AOAH)

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