Structure of PDB 5w4t Chain D

Receptor sequence

>5w4tD (length=315) Species: 7955 (Danio rerio) [Search protein sequence]

MNQPPRFQNYFFQSYLLVYEDTPVGTSITQLQAVDPDGEPLIFGVVGEEA
MRYFAVQGTTGVVWLRQPLDREAKSEMQVEFTVSDSQGVVKDTVNIQIGD
VNDNAPSFYNQPYAIQIPENTPVGTSVFMVNATDPDQGVGGSVLFSFQPP
SQFFSIDGARGIVTVTRALDYETTIAYQLTVNATDQDKRRPLSSLANLAI
TITDIQDMDPIFTNLPYSTNIMEDAPPGYEVRKIRAIDQDLGRPRGIGYT
IISGNTNSMFALDYISGSLTVSGQLDRENPLYSSGFIITVKATELNDDRT
PSSATVTTTFTILLI

3D structure

PDB

5w4t Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.

Chain

Resolution

2.65 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	CA	D	N101 N103 D133 D135 G139 D184	N102 N104 D134 D136 G140 D185
BS02	CA	D	Q205 M207 D237 D239 E293	Q206 M208 D238 D240 E294
BS03	CA	D	E118 E171 D203 I204 D206 D239	E119 E172 D204 I205 D207 D240
BS04	CA	D	E118 D169 E171 D206	E119 D170 E172 D207
BS05	CA	D	E19 E71 D99 V100 D102 D135	E20 E72 D100 V101 D103 D136
BS06	CA	D	E19 D69 E71 D102	E20 D70 E72 D103
BS07	CA	D	N1 Q2 D34 D36 E38 D84	N2 Q3 D35 D37 E39 D85

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:5w4t, PDBe:5w4t, PDBj:5w4t
PDBsum	5w4t
PubMed	30033219
UniProt	F1R7G8

[Back to BioLiP]