Structure of PDB 5vzu Chain D

Receptor sequence
>5vzuD (length=417) Species: 9606 (Homo sapiens) [Search protein sequence]
GRSLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCRE
EYGVCENLRKLEITGVSCRDVYAKLLHRYRHILGLWQPDIGPYGGLLNVV
VDGLFIIGWMYLPPHDPHVDDPMRFKPLFRIHLMERKAATVECMYGHKGP
HHGHIQIVKKDEFSTKCNQTDHHRMSGGRQEEFRTWLREEWGRTLEDIFH
EHMQELILMKFIYTSQYDNCLTYRRIYLPPSRPDDLIKPGLFKGTYGSHG
LEIVMLSFHGRRARGTKITGDPNIPAGQQTVEIDLRHRIQLPDLENQRNF
NELSRIVLEVRERVRQEQQEGQPFVLPVGVSSRNEDYPRTCRMCFYGTGL
IAGHGFTSPERTPGVFILFDEDRFGFVWLELKSFSLYSRVQATFRNADAP
SPQAFDEMLKNIQSLTS
3D structure
PDB5vzu Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
ChainD
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D H265 Y309 H312 K330 D334 N336 I337 I473 A474 W500 L503 H202 Y246 H249 K267 D271 N273 I274 I351 A352 W378 L381
BS02 ZN D C206 H214 C230 H236 C143 H151 C167 H173
External links
PDB RCSB:5vzu, PDBe:5vzu, PDBj:5vzu
PDBsum5vzu
PubMed29279382
UniProtQ5XUX0|FBX31_HUMAN F-box only protein 31 (Gene Name=FBXO31)

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