Structure of PDB 5vhd Chain D

Receptor sequence
>5vhdD (length=795) Species: 9913 (Bos taurus) [Search protein sequence]
RDSEYLLQENEPDATLDQQLLEDLQKKKTDLRYIEMQRFREKLPSYGMQK
ELVNMIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQP
RRISAISVAERVAAERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTTGI
ILQWLQSDPHLSSVSHIVLDEIHERNLQSDVLMTVVKDLLSYRPDLKVVL
MSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYVPEYYYE
AIYKERWPGYLRELRQRYSASTVDVVEMMDDEKVDLNLIAALIRYIVLEE
EDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFIIIPLHSLMPTVNQTQV
FKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTM
SAEWVSKANAKQRKGRAGRVQPGHCYHLYNSLRASLLDDYQLPEILRTPL
EELCLQIKILRLGGIAHFLSRLMDPPSNEAVLLSIKHLMELNALDKQEEL
TPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLG
KEKVADARRKELAKDTKSDHLTVVNAFKGWEKAKQRGFRYEKDYCWEYFL
SSNTLQMLHNMKGQFAEHLLGAGFVSSRNPQDPESNINSDNEKIIKAVIC
AGLYPKVAKIRLNMVKVYTKTDGVVAIHPKSVNVEQTEFNYNWLIYHLKM
RTSSIYLYDCTEVSPYCLLFFGGDISIQKQETIAVDEWIIFQSPARIAHL
VKELRKELDILLQEKIESPHPVDWKDTKSRDCAVLSAIIDLIKTQ
3D structure
PDB5vhd Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.
ChainD
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP D L209 G235 C236 G237 K238 T239 T240 R277 T561 D563 R607 V608 L43 G69 C70 G71 K72 T73 T74 R111 T373 D375 R419 V420
BS02 ALF D T234 E337 S559 R604 R607 T68 E171 S371 R416 R419
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:5vhd, PDBe:5vhd, PDBj:5vhd
PDBsum5vhd
PubMed29899445
UniProtQ05B79|DHX36_BOVIN ATP-dependent DNA/RNA helicase DHX36 (Gene Name=DHX36)

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