Structure of PDB 5uzw Chain D

Receptor sequence
>5uzwD (length=685) Species: 39387 (Gypsophila vaccaria) [Search protein sequence]
TSGFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQ
EKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQA
QNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSVT
IKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPNQEARYHFLGT
DQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLT
KLPNGLAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNN
PSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQ
HRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNLKIFRESV
VPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGF
GINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNV
FDDFISAAEYLISSGYTKARRVAIEGGSNGGLLVAACINQRPDLFGCAEA
NCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQ
PGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNP
IIARIQRKGRATMTQIAEVADRYGFMAKALEAPWI
3D structure
PDB5uzw Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants.
ChainD
Resolution2.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.-
3.4.21.26: prolyl oligopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D R81 F95 A102 N104 L132 F492 S493 A494 S495 T701 R79 F93 A100 N102 L130 F458 S459 A460 S461 T662
BS02 ZPR D H239 Y481 F484 S562 N563 L599 L602 W603 H218 Y447 F450 S528 N529 L565 L568 W569
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0046872 metal ion binding
GO:0070012 oligopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5uzw, PDBe:5uzw, PDBj:5uzw
PDBsum5uzw
PubMed28584123
UniProtR4P353

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