Structure of PDB 5uyy Chain D

Receptor sequence
>5uyyD (length=365) Species: 1392 (Bacillus anthracis) [Search protein sequence]
RKKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKELHVVDEI
AVDLQHACEEAHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKGS
IMNEAEALFSKEISFIGGHPMAGSHKTGVESAKAHLFENAFYILTPMHHV
PNEHVEELKDWLKGTGSHFLVLNTEEHDYVTGIVSHFPHLIAAGLVKQVE
KHAGDNPLIHQLAAGGFKDITRIASSSPKMWSDIVKQNREHLMVLLKEWI
SEMEDLYDTVSSGDAGEIQNYFADAKEYRDSLPVRKRGAIPAYHDLYVDV
LDKVGALAHVTSILAREEISITNLQILEAREGLLGVLRISFQREEDRMKA
KLALGEEKYQTYETI
3D structure
PDB5uyy Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.12: prephenate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TYR D K139 S333 I334 K126 S320 I321
BS02 TYR D V313 L314 D315 K316 A319 L320 V300 L301 D302 K303 A306 L307
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004665 prephenate dehydrogenase (NADP+) activity
GO:0008977 prephenate dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0070403 NAD+ binding
Biological Process
GO:0006571 tyrosine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5uyy, PDBe:5uyy, PDBj:5uyy
PDBsum5uyy
PubMed31750992
UniProtQ81P63

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