Structure of PDB 5uw0 Chain D

Receptor sequence
>5uw0D (length=633) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNK
ATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAP
KVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFL
GEVAHLDSQHAIVAHFHQWLAGVALPLCRKRRIDVVTIFTTHATLLGRYL
CASFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEA
EHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCF
DFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFI
VMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGL
TTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLI
LNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFP
SYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVD
RRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLE
YVKARQLALRRGYPDQFRELVGEELNDSNMDAL
3D structure
PDB5uw0 Activated state yGsy2p in complex with UDP-2-fluoro-2-deoxy-glucose
ChainD
Resolution2.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.11: glycogen(starch) synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP D G319 R320 K326 F480 Y492 E509 Y513 T514 E517 G314 R315 K321 F475 Y487 E504 Y508 T509 E512
BS02 G6P D Q283 H286 K290 H500 R580 R583 R587 Q278 H281 K285 H495 R575 R578 R582
Gene Ontology
Molecular Function
GO:0004373 alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity
GO:0005515 protein binding
GO:0016757 glycosyltransferase activity
GO:0042802 identical protein binding
GO:2001069 glycogen binding
Biological Process
GO:0005978 glycogen biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0042587 glycogen granule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5uw0, PDBe:5uw0, PDBj:5uw0
PDBsum5uw0
PubMed
UniProtP27472|GYS2_YEAST Glycogen [starch] synthase isoform 2 (Gene Name=GSY2)

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