Structure of PDB 5uty Chain D

Receptor sequence

>5utyD (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]

QGQLVQSGAELKKPGASVKISCKTSGYRFNFYHINWIRQTAGRGPEWMGW
ISPYSGDKNLAPAFQDRVIMTTDTEVPVTSFTSTGAAYMEIRNLKFDDTG
TYFCAKGLLRDGSSTWLPYLWGQGTLLTVSSASTKGPSVFPLAPSSKSTS
GGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVV
TVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKGLEVLF

3D structure

PDB

5uty Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.

Chain

Resolution

3.412 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	D	W50 D56	W50 D57
BS02	MAN	D	D99 G100 S100A	D111 G112 S113

External links

PDB	RCSB:5uty, PDBe:5uty, PDBj:5uty
PDBsum	5uty
PubMed	28275193

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