Structure of PDB 5ujt Chain D

Receptor sequence
>5ujtD (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
EDIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPL
FRRFRRFDPQFALTNIAVLKHNLNCVIKRSNSTAATNEVPEVTVFSKSPV
TLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFK
ISYLTFLPSDDEIYDCKVEHWGLDEPLLKHW
3D structure
PDB5ujt C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
ChainD
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D R52 R53 F58 N62 V65 H68 N69 C72 R76 R55 R56 F61 N65 V68 H71 N72 C75 R79
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5ujt, PDBe:5ujt, PDBj:5ujt
PDBsum5ujt
PubMed29255035
UniProtQ5Y7C3

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