Structure of PDB 5u06 Chain D

Receptor sequence
>5u06D (length=103) Species: 9606 (Homo sapiens) [Search protein sequence]
IHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHL
QKVKHYLILPSEERLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHC
CTR
3D structure
PDB5u06 Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
ChainD
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D R438 R458 S460 V468 K478 H479 Y480 L481 M495 R14 R34 S36 V44 K54 H55 Y56 L57 M69
External links
PDB RCSB:5u06, PDBe:5u06, PDBj:5u06
PDBsum5u06
PubMed29083893
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

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