Structure of PDB 5tx1 Chain D

Receptor sequence
>5tx1D (length=947) Species: 46928 (Human adenovirus 26) [Search protein sequence]
MMPQWAYMHIAGQDASEYLSPGLVQFARATDTYFSLGNKFRNPTVAPTHD
VTTDRSQRLTLRFVPVDREATTYLYKARFTLAVGDNRVLDMASTYFDIRG
VLDRGPSFKPYSGTAYNSLAPKGAPNPSQWETKEKQGTTGGVQQEKDVTK
TFGVAATGGINITNQGLLLGTDETAENGKKDIYADKTFQPEPQVGEENWQ
ENEAFYGGRALKKDTKMKPCYGSFARPTNEKGGQAKFKPVNEGEQPKDLD
IDFAYFDVPGGSPPAGGSGEEYKADIILYTENVNLETPDTHVVYKPGTSD
NSSEINLVQQSMPNRPNYIGFRDNFVGLMYYNSTGNMGVLAGQASQLNAV
VDLQDRNTELSYQLLLDSLGDRTRYFSMWNSAVDSYDPDVRIIENHGVED
ELPNYCFPLNGTGTNSTYQGVKITNGNDGAEESEWEKDDAISRQNQICKG
NVYAMEINLQANLWKSFLYSNVALYLPDSYKYTPANVKLPANTNTYEYMN
GRVVAPSLVDAYINIGARWSLDPMDNVNPFNHPRNAGLRYRSMLLGNGRY
VPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMILQSSLGNDLRVDG
ASVRFDSVNLYATFFPMAHNTASTLEAMLRNDTHDQSFNDYLSAANMLYP
IPAKATNVPISIPSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFVYSGSI
PYLDGTFYLNHTFKKVSIMFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYN
VAQCNMTKDWFLVQMLSHYNIGYQGFHVPEGYKDRMYSFFRNFQPMSRQV
VDEINYKDYKAVTLPFQHNNSGFTGYLAPTMRQGQPYPANFPYPLIGQTA
VPSVTQKKFLCDRVMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDMTF
EVDPMDEPTLLYLLFEVFDVVRVHQPHRGVIEAVYLRTPFSAGNATT
3D structure
PDB5tx1 Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses.
ChainD
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D A20 S21 V29 Q30 F31 R33 A34 Y38 G42 N43 N47 A15 S16 V24 Q25 F26 R28 A29 Y33 G37 N38 N42
BS02 peptide D D19 E22 P48 V50 P52 Y646 L647 S648 R676 R872 D14 E17 P43 V45 P47 Y641 L642 S643 R671 R867
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5tx1, PDBe:5tx1, PDBj:5tx1
PDBsum5tx1
PubMed28508067
UniProtQ3S8B3

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