Structure of PDB 5tgd Chain D

Receptor sequence

>5tgdD (length=238) Species: 1160233 (Brucella suis 92/29) [Search protein sequence]

VANCPVLVTGGARRIGKAIVEDLASHGFPVAIHCNRSLDEGEAIANRIND
SGGNACVVQADLEGDVRGLVKQASDRIGPIRLLVNNASLFQEDKVGALDM
ALWDRHFAVHLKTPVILAEDMRKALPEDQDGLVVNIIDQRVWKLNPQFFS
YTLSKSALWNATRTLAQALAPRIRVNAIAPGPTLPFERQVSKLPLQRAPE
LPEFGRTVRYFWENRSITGQMIALDGGQHLAWETPDIA

3D structure

PDB

5tgd Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis.

Chain

Resolution

1.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAP	D	R31 I32 H50 C51 N52 R53 S54 D78 L79 E80 N103 A104 S105 I153 I154 K172 P197 G198	R14 I15 H33 C34 N35 R36 S37 D61 L62 E63 N86 A87 S88 I136 I137 K155 P180 G181

External links

PDB	RCSB:5tgd, PDBe:5tgd, PDBj:5tgd
PDBsum	5tgd
PubMed	34981773

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