Structure of PDB 5nrv Chain D

Receptor sequence
>5nrvD (length=131) Species: 9606 (Homo sapiens) [Search protein sequence]
EYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFG
DGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGK
TFPDSLEDQLKPMLEWAHGGFKPTGIEGLKP
3D structure
PDB5nrv Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
ChainD
Resolution2.075 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 96K D I233 F236 W239 W263 D266 S270 I18 F21 W24 W48 D51 S55
External links
PDB RCSB:5nrv, PDBe:5nrv, PDBj:5nrv
PDBsum5nrv
PubMed
UniProtQ9UBC3|DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (Gene Name=DNMT3B)

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