Structure of PDB 5nbn Chain D

Receptor sequence
>5nbnD (length=359) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
VAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRDSYVGDEAQSKRGIL
TLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSN
REKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPI
YAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEK
LCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPS
VLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQK
EITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDES
GPSIVHHKC
3D structure
PDB5nbn The nuclear actin-containing Arp8 module is a linker DNA sensor driving INO80 chromatin remodeling.
ChainD
Resolution4.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP D G13 S14 K18 G156 D157 V159 K213 E214 G301 G302 M305 F306 K336 G9 S10 K14 G141 D142 V144 K198 E199 G286 G287 M290 F291 K321
BS02 LAR D M16 P32 Q59 Y69 D157 G182 T186 R206 E207 R210 M12 P28 Q44 Y54 D142 G167 T171 R191 E192 R195 BindingDB: IC50=70nM
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
Biological Process
GO:0000011 vacuole inheritance
GO:0006281 DNA repair
GO:0006338 chromatin remodeling
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
GO:0006897 endocytosis
GO:0009306 protein secretion
GO:0030010 establishment of cell polarity
GO:0030476 ascospore wall assembly
GO:1902404 mitotic actomyosin contractile ring contraction
Cellular Component
GO:0000142 cellular bud neck contractile ring
GO:0000785 chromatin
GO:0000812 Swr1 complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0030479 actin cortical patch
GO:0031011 Ino80 complex
GO:0032432 actin filament bundle
GO:0035267 NuA4 histone acetyltransferase complex
GO:0043232 intracellular non-membrane-bounded organelle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5nbn, PDBe:5nbn, PDBj:5nbn
PDBsum5nbn
PubMed30177756
UniProtP60010|ACT_YEAST Actin (Gene Name=ACT1)

[Back to BioLiP]