Structure of PDB 5naj Chain D

Receptor sequence
>5najD (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGR
KIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFA
SAMMHALEVL
3D structure
PDB5naj Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
ChainD
Resolution1.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8SE D T30 Q54 T29 Q53
BS02 8SE D M14 Y16 W23 N71 F77 Q79 R81 M13 Y15 W22 N70 F76 Q78 R80
External links
PDB RCSB:5naj, PDBe:5naj, PDBj:5naj
PDBsum5naj
PubMed33184177
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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