Structure of PDB 5n8v Chain D

Receptor sequence
>5n8vD (length=63) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
HSEREKRVSNAVEFLLDSRVRRTPTSSKVHFLKSKGLSAEEICEAFTKVG
QPKTLNEIKRILS
3D structure
PDB5n8v Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
ChainD
Resolution1.55 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 KZZ D N13 A14 E16 F17 T26 F34 K38 N10 A11 E13 F14 T23 F31 K35 MOAD: Ki=0.207uM
Gene Ontology
Biological Process
GO:0016560 protein import into peroxisome matrix, docking
Cellular Component
GO:0005778 peroxisomal membrane

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5n8v, PDBe:5n8v, PDBj:5n8v
PDBsum5n8v
PubMed28360328
UniProtQ8IEW2

[Back to BioLiP]