Structure of PDB 5n6u Chain D

Receptor sequence
>5n6uD (length=811) Species: 309799 (Dictyoglomus thermophilum H-6-12) [Search protein sequence]
MEILKLDGEWEFKAVKDKKWRKAKVPGCVHLDLMENGLIPDPFVGENELE
VQWVEKEDWIYRKKFQVGKEFLKYSSIYLEFEGIDTFSEIYLNGKKIGET
DNMFIAWEFNVKDLLVEGENELEVRLFSPSKVLEERAKNYPYKLHGGDYS
PRVFGRKAQYSFGWDWGPRLATSGIWKSVKLKGWNKARLLDVWVPVRSLG
ENAQINIELDIELQESIPVDVAFRISHKKPVLEQRLRFTLPEGRVFLKIP
LTIKNPKLWFPRGYGEQNLYTLQLVLLDEKGEVLDKVEERFGIRKVELFT
QEDNKGESFVFKINNIPVFAKGANWIPADSFLPRIKEEDYRLLLIRAKEA
GVNMLRVWGGGIYENDIFYELCDELGIMVWQDFMFACAEYPDDENFLNDV
QKEAEFVIKRLRNHPSIVLWCGNNCNHWGYYAKWWGEREKFWGEEIYSRV
LPDVCARLDLTRPYWPSSPYGGKDPNSQEVGDRHNWEVWHGWIDFNGYLK
DNGRFISEFGMQAPPVAETIRKFITSEKEYYPQSREMEFHNKAREGTERI
IRYIAGHFKITEDMNEYIYLSQIIQGLALKTGIEHWRNNKFHTSGSLIWQ
WNDCWPVVSWSIIDYYKKLKPSYYFVKRAFRDIKVNIEPRNGKLLVFGVN
DTLEKFYGKIEYAISTFRGKRRGKKEVDIEIPANSSVILGEFNLEDVDKF
KEFFYVQLYNEKDELIDQNEYFFAPFRHLELPNAVVVYSVKEIEENSYLL
NIESDFLALWVSLKLENAEWEDNFVNIYPKTKYSIRFKAPYTLKEVESKL
KLEGYNLKKVI
3D structure
PDB5n6u Is the acid/base catalytic residue mutation in beta-d-mannosidase DtMan from Dictyoglomus thermophilum sufficient enough to provide thioglycoligase activity?
ChainD
Resolution3.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.25: beta-mannosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA D W164 W486 H490 W599 W164 W486 H490 W599
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004567 beta-mannosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006516 glycoprotein catabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5n6u, PDBe:5n6u, PDBj:5n6u
PDBsum5n6u
PubMed28385558
UniProtB5YAN4

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