Structure of PDB 5n1x Chain D

Receptor sequence
>5n1xD (length=118) Species: 9606 (Homo sapiens) [Search protein sequence]
QIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLF
YSIFTDQLKRNLSVINLDPEINPEGFNILLDFMYTSRLNLREGNIMAVMA
TAMYLQMEHVVDTARKFI
3D structure
PDB5n1x Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors.
ChainD
Resolution1.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8HH D M51 Y58 M44 Y51 MOAD: Kd=689uM
BS02 8HH D N21 R24 L25 N14 R17 L18 MOAD: Kd=689uM
External links
PDB RCSB:5n1x, PDBe:5n1x, PDBj:5n1x
PDBsum5n1x
PubMed28485934
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

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