Structure of PDB 5n16 Chain D

Receptor sequence
>5n16D (length=129) Species: 5476 (Candida albicans) [Search protein sequence]
GAPKPPQEPDMNNLPENPIPQHQAKFVLNTIKAVKRNREAVPFLHPVDTV
KLNVPFYYNYIPRPMDLSTIERKINLKAYEDVSQVVDDFNLMVKNCKKFN
GEAAGISKMATNIQAQFEKLMVKVPPKEL
3D structure
PDB5n16 Selective BET bromodomain inhibition as an antifungal therapeutic strategy.
ChainD
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 8FN D D239 K242 L243 D48 K51 L52
BS02 8FN D P233 F234 V238 L243 C287 F290 N291 I297 P42 F43 V47 L52 C96 F99 N100 I106
External links
PDB RCSB:5n16, PDBe:5n16, PDBj:5n16
PDBsum5n16
PubMed28516956
UniProtQ5A4W8|BDF1_CANAL Bromodomain-containing factor 1 (Gene Name=BDF1)

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