Structure of PDB 5msm Chain D

Receptor sequence
>5msmD (length=370) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SINLHSAPEYDPSYKLIQLTPELLDIIQDPHQLRFKSLDKDKSEVVLCSH
DKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGFAKT
ESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENS
PCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQ
HLNVEDTHHAVGKDIEDEFNPYTREIIETVLNKFAVQEQNTWRLRIPFIA
QWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGYHFKP
TDKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEESRGMKIDS
FIMKYARRKRLGKKTVVTSR
3D structure
PDB5msm Structural studies of RFC(C)(tf18) reveal a novel chromatin recruitment role for Dcc1.
ChainD
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D M323 D324 M315 D316
BS02 peptide D S41 K44 D45 S47 V49 L60 K61 Q62 R63 K64 H65 S66 N67 F108 S37 K40 D41 S43 V45 L56 K57 Q58 R59 K60 H61 S62 N63 F104
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
GO:0007064 mitotic sister chromatid cohesion
GO:0034088 maintenance of mitotic sister chromatid cohesion
GO:0034398 telomere tethering at nuclear periphery
GO:0035753 maintenance of DNA trinucleotide repeats
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000785 chromatin
GO:0031390 Ctf18 RFC-like complex

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Biological Process

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Cellular Component
External links
PDB RCSB:5msm, PDBe:5msm, PDBj:5msm
PDBsum5msm
PubMed28188145
UniProtP25559|DCC1_YEAST Sister chromatid cohesion protein DCC1 (Gene Name=DCC1)

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