Structure of PDB 5mr0 Chain D

Receptor sequence
>5mr0D (length=290) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence]
MLYVYMDGEFVPENEAKVSIFDHGFLYGDGVFEGIRAYNGRVFRLKEHID
RLYDSAKAIDLEIPITKEEFMEIILETLRKNNLRDAYIRPIVTRGIGDLG
LDPRKCQNPSIIVITKPWGKLYGDLYEKGLTAITVAVRRNSFDALPPNIK
SLNYLNNILAKIEANAKGGDEAIFLDRNGYVSEGSGDNIFVVKNGAITTP
PTINNLRGITREAVIEIINRLGIPFKETNIGLYDLYTADEVFVTGTAAEI
APIVVIDGRKIGDGKPGEITRKLMEEFSKLTESEGVPIYE
3D structure
PDB5mr0 Thermostable Branched-Chain Amino Acid Transaminases From the ArchaeaGeoglobus acetivoransandArchaeoglobus fulgidus: Biochemical and Structural Characterization.
ChainD
Resolution1.98 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F32 G34 K150 E183 L206
Catalytic site (residue number reindexed from 1) F32 G34 K150 E183 L206
Enzyme Commision number 2.6.1.42: branched-chain-amino-acid transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PXG D G100 L101 G100 L101
BS02 PXG D R51 K150 Y154 E183 G186 D187 L206 I209 T210 G245 T246 R51 K150 Y154 E183 G186 D187 L206 I209 T210 G245 T246
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004084 branched-chain-amino-acid transaminase activity
GO:0008483 transaminase activity
GO:0052654 L-leucine-2-oxoglutarate transaminase activity
GO:0052655 L-valine-2-oxoglutarate transaminase activity
GO:0052656 L-isoleucine-2-oxoglutarate transaminase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009081 branched-chain amino acid metabolic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009098 L-leucine biosynthetic process
GO:0009099 L-valine biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5mr0, PDBe:5mr0, PDBj:5mr0
PDBsum5mr0
PubMed30733943
UniProtO29329|ILVE_ARCFU Putative branched-chain-amino-acid aminotransferase (Gene Name=ilvE)

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