Structure of PDB 5lb8 Chain D

Receptor sequence
>5lb8D (length=426) Species: 9606 (Homo sapiens) [Search protein sequence]
PERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLC
YQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKE
LLADLEREKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHC
VSQWGHDFRPDYLRLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKK
PVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKACGIVYCRTREAC
EQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFDKA
NVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIR
KEVAKLQEKRGNKASDKATIMAFDALVTFCEELGCRHAAIAKYFGDALPA
CAKGCDHCQNPTAVRRRLEALERSSS
3D structure
PDB5lb8 Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
ChainD
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C411 C431 C385 C405
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:5lb8, PDBe:5lb8, PDBj:5lb8
PDBsum5lb8
PubMed28100692
UniProtO94762|RECQ5_HUMAN ATP-dependent DNA helicase Q5 (Gene Name=RECQL5)

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