Structure of PDB 5kxe Chain D

Receptor sequence
>5kxeD (length=238) Species: 3922 (Wisteria floribunda) [Search protein sequence]
KETTSFVFTRFSPDPQNLLLQGDTVVTSSGHLQLTQVKDGEPVYSSLGRA
LYYAPIHIWDSNTDTVANFVTSFSFVIDAPNKAKAADGLAFFLAPVDTEP
QKPGGLLGLFHDDRHNKSNHIVAVEFDTFKNSWDPEGTHIGINVNSIVSR
KTISWDLENDEVANVVISYQASTKTLTASLVYPSSSTSYILNDVVDLKQI
LPEYVRVGFTAASGLSKDHVETHDVLAWTFDSDLPDPS
3D structure
PDB5kxe Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[ beta 14]GlcNAc), by Wisteria floribunda Agglutinin.
ChainD
Resolution2.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 6Y2 D D117 G135 F159 N161 G244 L245 S246 H249 D87 G105 F129 N131 G214 L215 S216 H219 MOAD: Kd=5.45uM
BS02 MN D E155 D157 D164 H169 E125 D127 D134 H139
BS03 CA D D157 F159 N161 D164 D127 F129 N131 D134
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5kxe, PDBe:5kxe, PDBj:5kxe
PDBsum5kxe
PubMed27601469
UniProtA0A1D5B395

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