Structure of PDB 5k0a Chain D

Receptor sequence

>5k0aD (length=322) Species: 1111708 (Synechocystis sp. PCC 6803 substr. Kazusa) [Search protein sequence]

SKNLDARLDTVYDAIVLGGGMGGLSAAIYLARYGLKCLVVEKGRGRSFWM
QDLRNYVGLDPDTPGRDIITHSTQQALHWGADLLRGYVEDVTDEGDTLAV
KVKVGKKDSLYPIFRTKYVIAATGIIDNLPQLEDMQNVYDYAGYTLHVCM
ICDGFDMWDQKAVLIAGTEGQINAAFVLNWFTPYITVLTHGLCTVGDEMK
AKLADHGYPLHEAAITKFLGEDHKMSGVELVDGTVMEATTGLINMGSVYH
NHYLKGIEGLEWDGENLVTNDMAQTSHPRIFALGDLKKGLNQVSVAVADG
TLAATQIWRNIRRASEPRKWIH

3D structure

PDB

5k0a Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase.

Chain

Resolution

1.706 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	D	G28 M29 G30 E49 K50 G53 R54 S55 M58 L61 R62 N63 Y95 V96 A130 T131 V156 C160 H258 G292 D293 Q300 V301	G20 M21 G22 E41 K42 G45 R46 S47 M50 L53 R54 N55 Y87 V88 A122 T123 V148 C152 H250 G284 D285 Q292 V293
BS02	FAD	D	K50 R52 W57 Y95 K111 G113 K114 L137 Y147	K42 R44 W49 Y87 K103 G105 K106 L129 Y139

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0004791	thioredoxin-disulfide reductase (NADPH) activity
GO:0016491	oxidoreductase activity

	Biological Process
GO:0045454	cell redox homeostasis
GO:0098869	cellular oxidant detoxification

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:5k0a, PDBe:5k0a, PDBj:5k0a
PDBsum	5k0a
PubMed	29133410
UniProt	P74746

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