Structure of PDB 5jk0 Chain D

Receptor sequence

>5jk0D (length=349) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence]

MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQ
ACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITERLAFNS
LKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKS
YIYNITLKNISKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIV
FTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLK
EWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGA
HMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHRLEEAASIWEE

3D structure

PDB

5jk0 Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.

Chain

Resolution

2.1 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	D	K26 L30 S31 L70 T74 Y75 I130 R213 S214 N215 Q285 Y289 K305 G307 H309	K26 L30 S31 L70 T74 Y75 I130 R205 S206 N207 Q277 Y281 K297 G299 H301	PDBbind-CN: Kd=150nM
BS02	dna	D	K62 R65 N66 S121 A123 T124 N127 S193 R199 N277 Q278 T284 A286 Y287 H335 A336	K62 R65 N66 S121 A123 T124 N127 S185 R191 N269 Q270 T276 A278 Y279 H327 A328	PDBbind-CN: Kd=150nM

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0009037	tyrosine-based site-specific recombinase activity

	Biological Process
GO:0006310	DNA recombination
GO:0007059	chromosome segregation
GO:0015074	DNA integration
GO:0051301	cell division

	Cellular Component
GO:0005737	cytoplasm

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:5jk0, PDBe:5jk0, PDBj:5jk0
PDBsum	5jk0
PubMed	28009253
UniProt	O25386\|XERH_HELPY Tyrosine recombinase XerH (Gene Name=xerH)

[Back to BioLiP]