Structure of PDB 5iqf Chain D

Receptor sequence
>5iqfD (length=301) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
RYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKT
KFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEI
KGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQN
VLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILR
MYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTY
K
3D structure
PDB5iqf Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2)-Ia.
ChainD
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.7.1.190: aminoglycoside 2''-phosphotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP D I208 G211 D213 I224 K226 Y274 I277 F281 H379 I392 D393 I31 G34 D36 I47 K49 Y97 I100 F104 H202 I215 D216
BS02 MG D H379 D393 H202 D216
External links
PDB RCSB:5iqf, PDBe:5iqf, PDBj:5iqf
PDBsum5iqf
PubMed27161980
UniProtP0A0C1|AACA_STAAU Bifunctional AAC/APH (Gene Name=aacA-aphD)

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