Structure of PDB 5hod Chain D
Receptor sequence
>5hodD (length=58) Species:
9606
(Homo sapiens) [
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RPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNR
RAKEKRLK
3D structure
PDB
5hod
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Chain
D
Resolution
2.682 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
dna
D
R89 T90 I92 R127 V131 W132 N135
R3 T4 I6 R41 V45 W46 N49
BS02
dna
D
R87 R89 K109 R115 Q134 R137
R1 R3 K23 R29 Q48 R51
Gene Ontology
Molecular Function
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677
DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:5hod
,
PDBe:5hod
,
PDBj:5hod
PDBsum
5hod
PubMed
28473536
UniProt
Q969G2
|LHX4_HUMAN LIM/homeobox protein Lhx4 (Gene Name=LHX4)
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