Structure of PDB 5hc2 Chain D

Receptor sequence
>5hc2D (length=343) Species: 77133 (uncultured bacterium) [Search protein sequence]
TNKIAEDPRIDPRIKAIFSGMDLGGGGDVESREAMLEAASSEEATAVRDG
LRVFLDACDNEEIAPSAGLKIEDYEFTSEPDGNIAKIQYIRPDSTDKLPC
VYYIHGGGMQSLSCYYGNYRAWGKIIASNGVAVAMVEFRNALVPSALPEV
APYPAGLNDCVSGVKWVASHADELGIDASRIIIAGEAGGGNLTLAAGLRL
KQEGSQDLIQGLYALCPYIAGSWPSEDSPSSTENNGILLDLHNNQGAMGY
GIEAYEMRDPLAWPGFATEEDVSGLVPTFISVNECDPLRDEGINFYRLLL
RAGVSAKCRQVMGTIHGTEIFPIACPDVSRDTAASIANFCKGG
3D structure
PDB5hc2 Structural insights of a hormone sensitive lipase homologue Est22.
ChainD
Resolution1.986 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) G108 G109 A188 Y219 W224 D287 H317
Catalytic site (residue number reindexed from 1) G107 G108 A187 Y218 W223 D286 H316
Enzyme Commision number 3.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NPO D G108 G109 A188 G189 Y219 L240 G107 G108 A187 G188 Y218 L239
Gene Ontology
Molecular Function
GO:0016298 lipase activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5hc2, PDBe:5hc2, PDBj:5hc2
PDBsum5hc2
PubMed27328716
UniProtH6BDX1

[Back to BioLiP]