Structure of PDB 5h9e Chain D

Receptor sequence
>5h9eD (length=318) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
SNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKS
GYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVD
EAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIR
VNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDQEFSSGV
FYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGDMVMVNFSD
MPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLS
VKQMPTLEQLKSWVRNNG
3D structure
PDB5h9e Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
ChainD
Resolution3.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna D N19 R20 D21 K27 S40 Q42 S43 R46 R49 M166 N18 R19 D20 K26 S39 Q41 S42 R45 R48 M165
BS02 dna D D109 A110 T168 D108 A109 T167
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5h9e, PDBe:5h9e, PDBj:5h9e
PDBsum5h9e
PubMed26863189
UniProtQ46899|CASC_ECOLI CRISPR system Cascade subunit CasC (Gene Name=casC)

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