Structure of PDB 5gwv Chain D

Receptor sequence
>5gwvD (length=333) Species: 67581,273057 [Search protein sequence]
DDDKMLAAEAANRDHVTRCVAQTGGSPDLVAHTAALRLYLRVPHFLTEWT
TDPDRRAAVSRALALDIVSMKLLDDLMDDDTGLDRVELACVCLRLHLRAL
HELESLARDPKAVTDILEQDAVHLCGGQIRTKRSRATNLREWRAHASTYG
STFLGRYGALAAACGGEGQPADSVREFAEAFAMTITMADDLTDYDRNGER
DGNLAHLMRTGAVAGQDVVDLLEELRGRALAAVAAPPGAPGLVPVVHLYT
DDVLVRLLPRHLGEAGAGAMATVKFKYKGEEKEVDISKIKKVWRVGKMIS
FTYDEGGGKTGRGAVSEKDAPKELLQMLEKQKK
3D structure
PDB5gwv Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism.
ChainD
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 78S D Y35 K67 D70 Q124 K128 Y145 F149 Y39 K71 D74 Q128 K132 Y149 F153
BS02 78S D R33 R37 Y245 R37 R41 Y249
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004521 RNA endonuclease activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:5gwv, PDBe:5gwv, PDBj:5gwv
PDBsum5gwv
PubMed30837154
UniProtA0A010;
P39476|DN7D_SACS2 DNA-binding protein 7d (Gene Name=sso7d)

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