Structure of PDB 5gpc Chain D

Receptor sequence
>5gpcD (length=190) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence]
KGPKYDQIIDAAVQVIAEHGYHQAQVSKIAKAAGVADGTIYLYFNNKEDV
LISLFQEKMGRFVDKIRSQMNEATDVEEKLKILVNMHFKQLAADHKLAIV
TQLELRQSNTELRLKINEVLKGYLNLLDELLMEGKEKGYFFQELDTRLAR
QMIFGTLDEVVTNWVMKDCKYDLTALVKPVHQLLLGGLRH
3D structure
PDB5gpc Structural basis of operator sites recognition and effector binding in the TetR family transcription regulator FadR.
ChainD
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D Q29 V30 Y45 N50 K51 Q25 V26 Y41 N46 K47 PDBbind-CN: Kd~100nM
BS02 dna D K8 A40 G42 T43 L46 Y47 K4 A36 G38 T39 L42 Y43 PDBbind-CN: Kd~100nM
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5gpc, PDBe:5gpc, PDBj:5gpc
PDBsum5gpc
PubMed28160603
UniProtQ9K8A4

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