Structure of PDB 5gie Chain D

Receptor sequence
>5gieD (length=230) Species: 10116 (Rattus norvegicus) [Search protein sequence]
LSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPPLSMLPHLADLVSYSIQ
KVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCG
SQDYKYDVTDVSTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR
PGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSL
NEEHSKQYRSLSFQPENSMKLTPLVLEVFG
3D structure
PDB5gie Regulation of the vitamin D receptor by vitamin D lactam derivatives.
ChainD
Resolution2.387 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D K242 S252 Q255 K260 P412 E416 K57 S67 Q70 K75 P223 E227
BS02 VDP D L223 S233 R270 S271 S274 W282 C284 V296 H393 Y397 L400 L38 S48 R85 S86 S89 W97 C99 V111 H204 Y208 L211 MOAD: Kd=769.2nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5gie, PDBe:5gie, PDBj:5gie
PDBsum5gie
PubMed27500498
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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