Structure of PDB 5f4p Chain D

Receptor sequence
>5f4pD (length=335) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
KTTLFCASDAKAYEKEVHNVWATHACVPTDPNPQEMVLANVTENFNMWKN
DMVEQMHEDIISLWDESLKPCVKLTGGSAITQACPKVSFDPIPLHYCAPA
GFAILKCNNKTFNGTGPCRNVSTVQCTHGIKPVVSTQLLLNGSLAEEEII
IRSENLTNNAKTIIVHLNESVNIVCTRPNNIRQAHCNINESKWNNTLQKV
GEELAKHFPSKTIKFEPSSGGDLEITTHSFNCRGEFFYCNTSDLFNGTYR
NGTYNHTGRSSNGTITLQCKIKQIINMWQEVGRAIYAPPIEGEITCNSNI
TGLLLLRDDTETFRPGGGDMRDNWRSELYKYKVVE
3D structure
PDB5f4p Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5VG D E370 I371 S375 F376 F382 N425 M426 W427 E429 G431 G473 M475 E224 I225 S229 F230 F236 N276 M277 W278 E280 G282 G318 M320 PDBbind-CN: -logKd/Ki=7.33,Kd=0.047uM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:5f4p, PDBe:5f4p, PDBj:5f4p
PDBsum5f4p
PubMed26985324
UniProtC6G099

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